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. 2005 Jul;49(7):2895–2902. doi: 10.1128/AAC.49.7.2895-2902.2005

TABLE 2.

Characteristics of the strains and their PBP and MurM sequence typesa

Strain Yr Source Serogroup MIC (μg/ml)
Sequence typeb
PenG AMX CTX CRO 1a 1b 2a 2b 2x 3 MurM
5204 1999 Sputum 14 6.0 6.0 12.0 3.0 C3 A5 A3 D1 C3 A1 A1
5268 2000 Blood 14 3.0 4.0 4.0 2.0 C3 A5 A3 D1′ C3 A1 A1
4843 1997 Trachea 23 2.0 1.5 1.0 1.0 C1 A3 A6 C1 C1 A1 A1
4790 1996 Blood 23 1.5 1.5 1.0 1.0 C1 A3 A6 C1 C1 A1 A1
5062 1999 Trachea 14 1.5 3.0 2.0 1.0 C3 A5 A3 ND ND A1 A1
5245 2000 Sputum 6 1.5 3.0 0.75 0.75 C2 A1 A4 E1 C2 A1 C1
5180 1999 Sputum 15 1.5 1.0 2.0 1.0 C1 A3 A6 C1 C1′ A1 A1
4883 1997 Blood 9 1.0 1.5 0.75 0.75 C1 A3 A3 C1 C1 A1 B1
5047 1999 Nose swab 9 0.75 0.50 2.0 0.50 C1 A4 A3 C1 C1 A1 A1
5104 1999 Sputum 23 0.50 0.50 0.75 0.50 C1 A3 A6 C1 C1 A1 A1
4935 1998 Blood 3 0.50 0.25 0.38 0.25 C1 A3 A6 C1 C1 A1 A1
5024 1999 Bronchus 15 0.25 0.094 0.38 0.38 A1 A2 ND F1 A5 A1 A1
5031 1999 Bronchus 23 0.25 0.19 0.19 0.125 C1 A3 A6 C1 C1 A1 A1
5259 2000 Trachea 15 0.19 0.023 0.094 0.064 B1 A3 A5 B1 B1 A2 A2
4816 1997 CSF 15 0.094 <0.016 0.064 0.032 B1 A3 A5 B1 B1 A2 A2
5023 1999 Blood 3 0.064 0.032 0.032 0.047 A1′′ A1 A1 A3 A3 A1 A1
4942 1998 Blood 6 0.047 0.064 0.032 0.047 A1 A3 A7 B2 A4 A1 A1
5084 1999 Eye swab ND 0.023 <0.016 <0.016 <0.016 A1 ND A8 A1′ A1′ A1 A1′
5074 1999 Blood 23 0.016 <0.016 <0.016 <0.016 A1′′ A3 A2 A1 A1 A1 A1
4910 1998 Pleural liquid 19 <0.016 <0.016 <0.016 0.016 A1′′ A1 A7 A1′′ A1 A1 A1
5075 1999 Blood 6 <0.016 <0.016 <0.016 <0.016 C1 A3 A9 A1 A1 A1 A2
5223 2000 Bronchus 6 <0.016 <0.016 <0.016 <0.016 A1′ A1 A4 A2 A2 A1 A1
R6 <0.016 <0.016 <0.016 <0.016 A1 A1 A1 A1 A1 A1 A1
R65031 1.0 0.75 0.75 0.5 C1 A3 A6 C1 C1 A1 A1
a

Data for isolates with identical sequences are highlighted in boldface. Abbreviations: CSF, cerebrospinal fluid; ND, not determined; PenG, penicillin G; AMX, amoxicillin; CTX, cefotaxime; CRO, ceftriaxome.

b

For PBP1a, PBP 2b, PBP 2x, and MurM, sequences that differed from each other by at most 10 residues are grouped under a capital letter, sequences that differed by at most a single residue are grouped under a single number, and primes denote single substitutions. For PBP 1b, PBP 2a, and PBP 3, each sequence that differs at a single position is designated by a number.