Table 1.

Predictors in 13 CLD risk prediction models validated in CKB

Model	Demographic		Lifestyle						Personal and family history			Blood-based biomarkers
	Age	Sex	Alcohol	BMI	Diet	PA	Smoking	WHR	Cirrhosis	Diabetes	Hepatitis	ALT	AST	GGT	TG
BARD				•						•		•	•
Cao-2021a	•	•	•	•					•b
CAP-Bc	•	•	•				•			•	•d	•		•
CLivD (lab)	•	•	•				•	•		•				•
CLivD (non-lab)	•	•	•				•	•		•
dAAR	•											•	•
DM-HCC	•													•	•
HLI			•	•	•	•	•			•	•
Li-2018e	•	•					•		•		•	•
Sinn-2020	•	•					•			•		•			•
Wen 1-2012	•	•	•			•	•			•
Wen 2-2012	•	•										•	•
Wen 3-2012	•	•	•			•	•			•		•	•

Abbreviations: ALT Alanine aminotransferase, AST Aspartate aminotransferase, BMI Body mass index, GGT Gamma-glutamyl transferase, HBV Hepatitis B virus, HCV Hepatitis C virus, PA Physical activity, TG Triglycerides, WHR Waist-to-hip ratio

^aPsychological trauma was included as an additional predictor in Cao-2021

^bCirrhosis was defined as medical history of liver diseases in mothers

^cAdditional predictors included income, statin exposure, and antiplatelet

^dHepatitis was defined as hepatitis C

^eAdditional predictors included HbA1c, antidiabetes medication, antihyperlipidemia medication, and THR, which was included as an additional predictor in Li-2018