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. 2024 Dec 31;30:284. doi: 10.1186/s10020-024-01037-w

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — The irradiation device and the target areas for tumor irradiation. A Laser location (Red) during irradiation. B Simulated photographs of conventional radiotherapy (CNRT) and reduced tumor area radiotherapy (RTRT) of mouse tumors (Green). C Stability of irradiation dose for small area irradiation. The gray line represents the theoretical value of irradiation. D Schematic of mouse tumor irradiation in a unilateral model. Blue: tumor. Red: irradiated target areas. E Schematic of mouse tumor irradiation in a bilateral model. Blue: tumor. Red: irradiated target areas