Fig. 4.

Downregulation of X-linked genes is impacting dosage compensation. a) The relationship between normalized expression of dosage compensated (circles) and not dosage compensated (triangles) X-linked genes in wild-type hermaphrodites/females (XX individuals) versus differential gene expression in males. Genes with significant differential gene expression in males only are shown in blue, and shared genes are shown in purple. Both axes are plotted on a log₂ scale. b) The relationship between normalized expression of dosage compensated (circles) and not dosage compensated (triangles) X-linked genes in wild-type hermaphrodites/females (XX individuals) versus differential gene expression in females. Genes with significant differential gene expression in females only are shown in pink, and shared genes are shown in purple.