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. 2024 Dec 31;22:1164. doi: 10.1186/s12967-024-05970-6

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — RBM47 overexpression protected PC cells from NK cells-mediated tumor cell killing. A The schematic diagram of co-culture of NK cells and PC cells. B The CCK-8 assay for cell viability of PC cells. C The LDH release assay for cytotoxic activity of NK cells. D The content of Granzyme B, MIP-1α, IFN-γ in supernatant of co-culture system NK and PC cells. *p < 0.05, **p < 0.01 versus OE-RBM47^Dox− or shRBM47^Dox−