Fig. 8.

PDIA6 overexpression compromised the tumor-inhibiting effect of RBM47 knockdown on PC cells. A The mRNA level of PDIA6 expression in PC cells (normalized by GAPDH). B The CCK-8 assay for cell viability of PC cells. C Flow cytometry analysis for the percentage of EdU-positive PC cells. D The CCK-8 assay for cell viability of PC cells. E The content of Granzyme B and IFN-γ in supernatant of co-culture system consisting of NK and PC cells. F Western blot for PDIA6 expression. G Quantification of the protein levels of CTTN and PD-L1 expression in F. *p < 0.05, **p < 0.01 versus Control or shNC^Dox+ + EV, ^#p < 0.05, ^##p < 0.01 versus EV or shRBM47^Dox+ + EV