Table 2.

Linear associations between epilepsy and brain function

Brain function	Beta	P	FDR-Q
Cognitive function
Numeric memory	−0.217	< 0.001	< 0.001
Fluid intelligence	-0.173	< 0.001	< 0.001
Prospective memory	−0.157	< 0.001	< 0.001
Reaction time	0.271	< 0.001	< 0.001
Motor function
Hand grip strength (left)	−0.190	< 0.001	< 0.001
Hand grip strength (right)	−0.202	< 0.001	< 0.001
Usual walking pace	−0.203	< 0.001	< 0.001
Falls in the last year	0.370	< 0.001	< 0.001
Mental health
General mental status	0.128	< 0.001	< 0.001
Depression (PHQ−4 score)	0.184	< 0.001	< 0.001
Depression (PHQ−9 score)	0.242	< 0.001	< 0.001
Depression (CIDI score)	0.058	0.365	0.411
Anxiety (GAD−7 score)	0.107	0.003	0.005
Life satisfaction	0.213	< 0.001	< 0.001
Subjective well-being	0.115	0.002	0.003
Unusual and psychotic experiences	0.120	0.418	0.418
Traumatic events	0.120	0.023	0.030

Note: The model was adjusted for age, sex, ethnicity, qualification, BMI, socioeconomic status, smoking status, alcohol drinker status. FDR-Q is the association P-value adjusted for the false discovery rate. PHQ-4, Personal Health Questionnaire-4; CIDI, Composite International Diagnostic Interview; GAD−7: Generalized Anxiety Disorder−7