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. 2005 Jul;49(7):2845–2850. doi: 10.1128/AAC.49.7.2845-2850.2005

TABLE 2.

Minimal effective concentrations obtained by a radial diffusion assay for LL-37, fragments 106 and 110, the 18-mer LLKKK, and BMAP-27 for gram-negative and -positive bacteria and C. albicansa

Pathogen NaCl concn (mM) Minimal effective concn (μM)
LL-37 Fr 106 Fr 110 18-mer BMAP-27
E. coli 0 0.26 0.40 0.33 0.33 0.14
150 1.2 0.42 0.47 0.66 0.50
P. aeruginosa 0 0.18 0.26 0.18 0.29 0.20
150 0.19 0.22 0.15 0.06 0.10
S. aureus 0 1.5 0.86 0.8 1.2 0.67
150 4.6 2.6 2.4 0.39 0.45
C. albicans 0 10 5.1 2.4 2.2 0.36
150 >40 >40 >40 >40 >40
a

The values were determined at a low (0 mM) or physiological (150 mM) concentration of NaCl. Each value is based on data from three independent experiments.