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. 2024 Dec 30;22:1158. doi: 10.1186/s12967-024-06020-x

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 2 — TAL modulates intracellular signaling pathways. A, B Functional annotation of the striatal transcriptome using Eggnog. C, D KEGG enrichment analysis of transcripts. DEGs are divided into 10 KEGG pathway terms along the y-axis. E Ranking of KEGG pathways based on the number of genes associated with selected genes. The top 10 pathways with the highest gene count are displayed. Squares represent KEGG pathways, circles represent mRNAs, and the color and size indicate the number of transcripts connected to each node