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. 2024 Dec 30;22:1158. doi: 10.1186/s12967-024-06020-x

Fig. 4.

Fig. 4

TAL regulates the expression of both TRHR and TH in the striatum. A, B, C Western blot analysis of TRHR and TH levels in the striatum of different groups of rats.Differential analysis of TRHR B and TH C in the striatum of different groups (N = 8/group; error bars represent SEM). Statistical significance: ****P < 0.0001, one-way ANOVA followed by Tukey's test. D Immunohistochemical images of TRHR in the striatum of different groups of rats (CTR-Int, CTR-Les, TAL-Les). Scale bar: 200 µm. E Differential analysis of TRHR-positive cell counts in the striatum of different groups (N = 8/group; error bars represent SEM). Statistical significance: ****P < 0.0001, one-way ANOVA followed by Tukey's test. F Immunofluorescence staining and colocalization of TH and TRHR in the striatum of various animal groups. Scale bar: 20 µm