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. 2024 Dec 30;22:1158. doi: 10.1186/s12967-024-06020-x

Fig. 6.

Fig. 6

TAL enhances the expression of RARα and DRD2 in the striatum. A, B Immunofluorescence staining of TRHR and RARα in the striatum of different groups of rats (CTR-Int, CTR-Les, TAL-Les). Scale bar: 25 μm. C, D Analysis of relative fluorescence intensity (N = 8/group; error bars represent SEM). Statistical significance: ****P < 0.0001, one-way ANOVA followed by Tukey's test. E Immunofluorescence colocalization of DRD2 and RARα in the striatum. F Western blotting analysis of P-ERK1/2, ERK1/2, RARα, and DRD2 levels in the striatum of different groups of rats. G, H, I Differential analysis of P-ERK1/2, RARα, and DRD2 in the striatum of different groups (N = 8/group; error bars represent SEM). Statistical significance: ****P < 0.0001, one-way ANOVA followed by Tukey's test