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. 2024 Dec 31;17:132. doi: 10.1186/s13045-024-01651-5

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 2 — Efficacy of IBI110 in combination with sintilimab and chemotherapy in sqNSCLC and GC patients. (A) Confirmed best overall response in sqNSCLC: 1 patient had increase of 11.04% in size of the target lesion and 1 patient had decrease of 38.66% in size of the target lesion, but their overall responses were PD due to the presence of new lesions. (B) Tumor assessment in patients with sqNSCLC: 1 patient had the first and second tumor assessment of iUPD, and continued treatment until the third tumor assessment of iCPD. (C) Confirmed best overall response in GC: 1 patient had decrease of 0.83% in size of the target lesion, but the overall response was PD due to the presence of new lesion. (D) Tumor assessment in patients with GC