Table 1.
Preoperative Baseline Characteristics of Patients in the Two Groups
| Baseline Characteristics | Total | Non-POCD | POCD | P-value |
|---|---|---|---|---|
| Age (years) | 55.47 ± 11.75 | 54.72 ± 11.84 | 57.43 ± 11.34 | 0.047 |
| BMI (kg/m2) | 23.42 ± 3.60 | 23.43 ± 3.55 | 23.39 ± 3.74 | 0.937 |
| Educational level (years) | 9.04 ± 2.39 | 10.03 ± 1.75 | 6.46 ± 1.88 | 0.001 |
| Male | 204 (54.8) | 151 (40.6) | 53 (14.2) | 0.243 |
| Female | 168 (45.2) | 118 (31.7) | 50 (13.4) | |
| Smoking | 116 (31.2) | 82 (22.0) | 34 (9.1) | 0.363 |
| Drinking | 129 (34.7) | 92 (24.7) | 37 (9.9) | 0.422 |
| Hypertension | 102 (27.4) | 73 (19.6) | 29 (7.8) | 0.470 |
| Diabetes | 33 (8.9) | 26 (7.0) | 7 (1.9) | 0.257 |
| Coronary heart disease | 40 (10.8) | 31 (8.3) | 9 (2.4) | 0.283 |
| Cerebrovascular disease | 31 (8.3) | 20 (5.4) | 11 (3.0) | 0.208 |
| LVEF (%) | 62.71 ± 9.17 | 63.21 ± 8.53 | 61.40 ± 10.60 | 0.090 |
| Scr (umol/L) | 78.27 ± 30.43 | 76.84 ± 29.85 | 82 ± 31.73 | 0.144 |
| D-dimer (umol/L) | 1.39 ± 2.14 | 1.38 ± 2.06 | 1.42 ± 2.36 | 0.869 |
| GHb (%) | 5.875 ± 0.80 | 5.91 ± 0.84 | 5.77 ± 0.67 | 0.118 |
| Hs-CRP (mg/L) | 10.14 ± 3.30 | 8.92 ± 2.96 | 13.32 ± 1.63 | 0.001 |
| Glucose (mg/dl) | 5.21 ± 1.57 | 5.17 ± 1.41 | 5.32 ± 1.94 | 0.414 |
| HDL (mmol/L) | 1.11 ± 0.30 | 1.10 ± 0.30 | 1.14 ± 0.28 | 0.190 |
| LDL (mmol/L) | 2.84 ± 1.21 | 2.78 ± 0.75 | 3.00 ± 1.95 | 0.110 |
| Triglyceride (mmol/L) | 1.38 ± 1.03 | 1.41 ± 1.12 | 1.29 ± 0.72 | 0.291 |
| Serum albumin (g/dl) | 38.54 ± 4.15 | 38.78 ± 4.06 | 37.93 ± 4.35 | 0.079 |
| WBC (10^9/L) | 6.72 ± 2.52 | 6.69 ± 2.59 | 6.82 ± 2.34 | 0.645 |
| Neutrophil (10^9/L) | 4.23 ± 2.42 | 4.18 ± 2.49 | 4.36 ± 2.23 | 0.507 |
| Lymphocyte (10^9/L) | 1.83 ± 0.65 | 1.86 ± 0.65 | 1.77 ± 0.67 | 0.262 |
| PLT (10^9/L) | 205.92 ± 60.84 | 209.74 ± 58.76 | 195.94 ± 65.21 | 0.050 |
| RBC (10^12/L) | 4.40 ± 0.68 | 4.45 ± 0.66 | 4.28 ± 0.69 | 0.025 |
| Hemoglobin (g/L) | 129.55 ± 21.50 | 130.64 ± 20.66 | 126.71 ± 23.42 | 0.115 |
| MV (hours) | 26.04 ± 26.55 | 19.14 ± 14.47 | 44.07 ± 39.50 | 0.000 |
| Operation duration (Minutes) | 365.55 ± 105.19 | 364.70 ±103.36 | 367.78 ± 110.31 | 0.801 |
| Duration of CPB (Minutes) | 147.96 ± 56.64 | 144.91 ± 56.75 | 155.90 ± 55.83 | 0.094 |
| Duration of ACC (Minutes) | 91.65 ± 70.97 | 87.30 ± 43.23 | 102.97 ±114.88 | 0.057 |
Abbreviations: POCD, Postoperative cognitive dysfunction; BMI, Body Mass Index; LVEF, Left Ventricular Ejection Fraction; SCr, Serum creatinine; GHb, Glycosylated hemoglobin; Hs-CRP, Hypersensitive C-reactive protein; LDL, Low-Density Lipoprotein Cholesterin; HDL, High-Density Lipoprotein cholesterol; WBC, White Blood Cell; PLT, Blood Platelet Count; RBC, Red Blood Cell; MV, Mechanical Ventilation; CPB, Cardiopulmonary bypass; ACC, Aortic occlusion.