TABLE 2.
Frequencies of mbl2 SNPs and haplotypes in persons recovered from hepatitis B and those with viral persistence
| Genotype | % Of chromosomesa with the indicated genotype in:
|
OR | 95% CI | P | |
|---|---|---|---|---|---|
| Recovered subjects (n = 648-676) | Subjects with viral persistence (n = 372-378) | ||||
| SNPs | |||||
| −550G | 33.0 | 29.3 | 0.82 | 0.61-1.09 | 0.17 |
| −221C (X allele) | 17.7 | 23.4 | 1.38 | 1.01-1.89 | 0.04 |
| Codon 52T | 6.7 | 6.6 | 0.97 | 0.58-1.61 | 0.90 |
| Codon 54A | 10.0 | 13.4 | 1.35 | 0.90-2.03 | 0.15 |
| Codon 57A | 6.8 | 5.9 | 0.95 | 0.53-1.68 | 0.85 |
| Haplotypes | |||||
| YA | 59.8 | 51.9 | 0.73 | 0.56-0.94 | 0.02 |
| XA | 17.5 | 23.0 | 1.40 | 1.03-1.92 | 0.03 |
| O | 40.9 | 44.1 | 1.14 | 0.78-1.66 | 0.50 |
a
n is the total number of chromosomes for which genotypes were determined and varies slightly due to the failure of some specimens to amplify for a particular SNP.