Table 2.

Yields and Chemical Characterization of Triazoloquinazoline Derivatives

compd no.	% yield	mp (°C)	MS	formula	anal.
3	29	184–185	EI: 375	C20H14N5O2Cl·0.81H2O	C,H,N
4	12	258–260	EI: 433	C22H16N5O3Cl·0.53CH2Cl2	C,H,N
5	25	210–211	CI: 545	C21H14N6O2ClI	C,H,N
6	45	197–199	EI: 418	C21H15N6O2Cl·0.64H2O	C,H,N
7	22	280–282	EI: 529	C21H13N5O2ClI·0.94(CH3)2CO	C,H,N
8	16	224–227	CI: 530	C21H13N5O2ClI·1.17(CH3)2CO	C,H,N
9	51	260–262 dec	EI: 529	C21H13N5O2ClI	C,H,N
10	33	248–250	CI: 438	C21H13N5O2Cl2	C,H,N
11	38	207–209 dec	EI: 417	C22H16N5O2Cl	C,H,N
12	58	115–118	EI: 417	C22H16N5O2Cl	C,H,N
13	57	205–207	CI: 480	C27H18N5O2Cl	C,H,N
14	100	175–178	EI: 493	C28H20N5O2Cl	C,H,N
15	65	253–255	EI: 417	C22H17N5O2Cl	C,H,N
16	43	305–307	CI: 416	C21H15N5O2Cl	C,H,N
17	13	131–134	CI: 457	C21H21N6O4Cl	C,H,N
18	15	220	CI: 457	C21H21N6O4Cl·2.6CH3OH	C,H,N
19	50	216–218	CI: 457	C21H21N6O4Cl	C,H,N
21	53	189–192	CI: 485	C23H25N6O4Cl	C,H,N
22	100	196–198	CI: 499	C24H27N6O4Cl	C,H,N
23	100	156–157	EI: 512	C25H29N6O4Cl·0.91H2O	C,H,N
24	56	175–176	FAB: 357	C16H13N6O2Cl	FAB+a
25	71	278	FAB: 357	C16H13N6O2Cl	FAB+a
26	72	137–139	EI: 356	C16H13N6O2Cl·CF3COOH	C,H,N
28	64	231–232	FAB: 385	C18H17N6O2Cl	FAB+a
29	80	153–155	CI: 399	C19H19N6O2Cl·CF3COOH·0.87CH3OH	C,H,N
30	70	165–167	EI: 412	C20H21N6O2Cl	FAB+a
31	71	149–151	EI: 503	C26H22N5O4Cl·CF3COOH	C,H,N
32	54	185–187	EI: 399	C18H14N5O4Cl·0.3EtOAc	C,H,N
33	62	165	EI: 455	C22H22N5O4Cl·0.37(C2H5)2O	C,H,N
34	26	209–211	FAB: 400	C18H14N5O4Cl·0.56CH2Cl2	C,H,N

^aHigh-resolution mass in FAB⁺ mode (m/z) determined to be within acceptable limits. 24: calcd, 357.0867; found, 357.0879. 25: calcd, 357.0867; found, 357.0865. 28: calcd, 385.1180; found, 385.1168. 30: calcd, 413.1491; found, 413.1493.