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Macroscopic illustration of acetic acid-induced colitis in rats. (a) Normal; (b) control: colitis features, including thickness, edema, erythema, and necrosis of tissue, are evident; (c) normal dose of four vitamins (B1, B2, B6, and B12); (d) mega (×10 of normal) dose of four vitamins; (e) mega dose of vitamin B1; (f) mega dose of vitamin B2; (g) mega dose of vitamin B6; (h) mega dose of vitamin B12; (i) mesalazine (150 mg/kg); and (j) dexamethasone (1 mg/kg)
