FIG. 4.

Lung histopathology of hMPV- and sham-infected mice and cotton rats. (A) Six mice per group were sacrificed at different times postinfection, and their lungs were removed and fixed with 10% formalin. Thin sections of paraffin-embedded lung tissues were cut and stained with hematoxylin and eosin. A representative section (magnification, ×10) is shown for sham-infected mice on day 3 and hMPV-infected mice on days 3, 5, 7, 12, and 21 postinfection. Lung histopathology of sham-infected mice at different time points was similar to that shown on day 3. (B) Representative sections (magnification, ×20) of cotton rat lungs are shown for sham-infected rats on day 3 and for the same days postinfection as the mice.