Table 2. Hematological Parameters of Podoconiosis Patients and Controls in West Gojjam Zone, Ethiopia.
| Variables | Patients (N = 53) | Controls (N = 67) | MD (95% CI) | p-value | AMD (95% CI) | p-value |
|---|---|---|---|---|---|---|
| Mean (SD) | Mean (SD) | |||||
| RBC (x10^12/L) | 4.85 (0.39) | 5.12 (0.50) | -0.27 (-0.44, -0.10) | 0.002 | -0.15 (-0.34, 0.03) * | 0.105 |
| WBC (x10^9/ L) | 5.86 (2.00) | 7.39 (2.63) | -1.53 (-2.39, -0.66) | 0.001 | -1.15 (-2.09, -0.21) ** | 0.017 |
| HGB (g/dL) | 12.06 (0.94) | 14.14 (1.59) | -2.07 (-2.57, -1.59) | <0.001 | -1.73 (-2.28, -1.19) *** | <0.001 |
| PLT (x10^9/ L) | 248.66 (97.62) | 261.83 (91.20) | -13.17 (-47.42, 21.07) | 0.448 | -25.45 (-60.68, 9.79) **** | 0.257 |
| MPV (fl) | 13.44 (13.90) | 11.34 (1.61) | 2.10 (-1.42, 5.63) | 0.239 | 1.78 (-1.98, 5.53) ***** | 0.35 |
| Abs Lymphocyte (x10^9/ L) | 2.99 (0.92) | 2.09 (1.13) | 0.90 (0.45, 1.35) | <0.001 | 0.98 (0.50, 1.46) ****** | <0.001 |
| Abs Monocyte (x10^9/ L) | 1.26 (0.86) | 0.86 (0.92) | 0.40 (0.07, 0.72) | 0.016 | 0.54 (0.22, 0.85) ******* | 0.001 |
| Abs Neutrophil (x10^9/ L) | 0.72 (0.85) | 4.38 (2.33) | -3.67 (-4.34, -2.99) | <0.001 | -3.42 (-4.15, -2.69) ******** | <0.001 |
| Abs Eosinophil (x10^9/ L) | 0.33 (0.37) | 0.51 (0.48) | -0.18 (-0.34, -0.03) | 0.026 | -0.20 (-0.37, -0.03) ********* | 0.019 |
| Abs Basophil (x10^9/ L) | 0.023 (0.037) | 0.025 (0.058) | -0.001 (-.02, 0.02) | 0.871 | -0.004 (-0.02, 0.02) ********** | 0.691 |
| MCV (fl) | 93.98 (3.47) | 92.18 (4.32) | 1.79 (0.35, 3.24) | 0.015 | 1.88 (0.38, 3.81) *********** | 0.014 |
| MCH (pg) | 24.85 (0.97) | 27.66 (1.85) | -2.81 (-3.37, -2.25) | <0.001 | -2.81 (-3.41, -2.11) *********** | <0.001 |
| MCHC (g/dl) | 26.45 (0.38) | 30.03 (2.03) | -3.58 (-4.14, -3.02) | <0.001 | -3.57 (-4.19, -2.94) ************* | <0.001 |
| CD4 # | 673.58 (224.46) | 681.13 (246.78) | -7.55 (-93.89, 78.80) | 0.863 | 40.06 (-54.94, 135.06) ************* | 0.405 |
| CD4% | 34.89 (7.54) | 37.61 (8.56) | -2.72 (-5.68, 0.24) | 0.071 | -3.39 (-6.39, -0.40) *************** | 0.027 |
RBC = Red Blood Cell Count, WBC = White Blood Cell Count, HGB = Hemoglobin, PLT = Platelet Count, MPV = Mean Platelet Volume, Abs = Absolute
MCV = Mean Corpuscular Volume, MCH = Mean Corpuscular Hemoglobin, MCHC = Mean Corpuscular Hemoglobin Concentration, AMD = Adjusted mean difference
All AMD were adjusted for between-subject effects with p < 0.5
*Adjusted for Age, Education Level, Leg Washing, Shoe Wearing, and Monthly Income
**Adjusted for Education Level, Leg Washing, Shoe Wearing, Monthly income, Occupation, and Marital Status
***Adjusted for Age, Leg Washing, Shoe Wearing, Monthly Income, and Marital Status
****Adjusted for Shoe Wearing and Education Level
*****Adjusted for Age and Shoe Wearing
******Adjusted for Shoe Wearing, Education Level, Occupation, Marital Status, and Monthly Income
*******Adjusted for Shoe Wearing and Monthly Income
********Adjusted for Age, Occupation, Marital Status, Leg Washing, and Monthly Income
*********Adjusted for Occupation, Monthly Income, Marital Status, and Shoe Wearing
**********Adjusted for Education Level, Monthly Income, Marital Status, and Shoe Wearing
***********Adjusted for Monthly Income, Marital Status, Education Level, and Leg Washing
************Adjusted for Age, Occupation, Education Level, Marital Status, and Monthly Income
*************Adjusted for Age, Occupation, Leg Washing, and Monthly Income
**************Adjusted for Age, Occupation, Leg Washing, Shoe Wearing, and Marital Status
*************** Adjusted for Shoe Wearing and Educational Level