Table 3. Immunological Factors of Podoconiosis Patients and Controls in West Gojjam Zone, Ethiopia.
| Patients (N = 53) | Controls (N = 67) | MD (95% CI) | p-value | AMD (95% CI) | p-value | |
|---|---|---|---|---|---|---|
| Variables | Mean (SD) | Mean (SD) | ||||
| ln [TNFa] | 0.47 (1.14) | 0.78 (1.17) | -0.31 (-0.73, 0.11) | 0.147 | -0.26 (-0.71, 0.18) * | 0.246 |
| ln [IL17] | 0.20 (0.73) | 0.23 (0.58) | -0.02 (-0.26,0.21) | 0.842 | 0.02, (-0.23, 0.27) ** | 0.885 |
| ln [IL10] | 1.33 (2.14) | 1.54 (2.07) | -0.21 (-0.97, 0.56) | 0.592 | -0.31 (-1.14, 0.52) *** | 0.465 |
| ln [IL4] | 0.69 (1.45) | 0.61 (1.41) | 0.09 (-0.43, 0.61) | 0.739 | 0.03 (-0.53, 0.59) **** | 0.903 |
| ln [IFN-y] | 0.16 (0.85) | 0.15 (0.87) | 0.01 (-0.29, 0.33) | 0.929 | 0.05 (-0.25, 0.34) ***** | 0.749 |
| ln [IL6] | 0.90 (0.82) | 0.81 (0.87) | 0.09 (-0.22, 0.40) | 0.552 | -0.01 (-0.36, 0.34) ****** | 0.972 |
| ln [TGF-B] | 6.73 (0.32) | 6.66 (0.35) | 0.07 (-0.05, 0.19) | 0.279 | 0.07 (-0.06, 0.21) ******* | 0.292 |
All Immunological Variables were logarithmically adjusted using ln[x), TNF-a = Tumor Necrosis Factor alpha, IL = Interleukin, IFN-y = Interferon gamma, TGF-B = Transforming Growth Factor Beta, AMD = Adjusted Mean difference
* Adjusted for Age, Education Level, Occupation, Marital Status, and Monthly Income
**Adjusted for Age, Education Level, Occupation, Monthly Income, and Shoe Wearing
***Adjusted for Occupation, Shoe Wearing, and Leg Washing
****Adjusted for Let Washing, Marital Status, and Monthly Income
*****Adjusted for Marital Status, Shoe Wearing, and Monthly Income
******Adjusted for Age, Marital Status, Occupation, Leg Washing, and Monthly Income
*******Adjusted for Occupation, Education Level, Leg Washing, and Shoe Wearing