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. 2024 Dec 18;11:1486611. doi: 10.3389/fmed.2024.1486611

Table 2.

Association of covariates and osteoporosis risk.

Variables OR (95% CI) p_value
Age 1.09 (1.07, 1.11) <0.001
Gender
Male 1 (reference)
Female 4.67 (3.68, 5.94) <0.001
Race
Non-Hispanic White 1 (reference)
Non-Hispanic Black 0.35 (0.24, 0.50) <0.001
Mexican American 0.84 (0.61, 1.15) 0.265
Other Hispanic 1.03 (0.69, 1.53) 0.902
Other Race* 1.46 (1.05, 2.04) 0.024
PIR 0.79 (0.73, 0.85) <0.001
Education level
Less than high school 1 (reference)
High school or equivalent 0.80 (0.61, 1.05) 0.100
Above high school 0.60 (0.47, 0.75) <0.001
Smoking status
Never 1 (reference)
Former 0.59 (0.47, 0.74) <0.001
Now 1.15 (0.83, 1.59) 0.383
Drinking status
Never 1 (reference)
Former 0.67 (0.51,0.87) 0.004
Mild 0.47 (0.36,0.61) <0.001
Moderate 0.42 (0.26,0.68) <0.001
Heavy 0.71 (0.44,1.14) 0.151
CVD
No 1 (reference)
Yes 1.19 (0.93,1.53) 0.173
Hypertension
No 1 (reference)
Yes 0.93 (0.73,1.18) 0.545
DM
No 1 (reference)
Yes 0.71 (0.55,0.93) 0.013
HbA1c (%) 0.80 (0.71,0.91) 0.001
ALT (u/L) 0.97 (0.95,0.98) <0.001
AST (u/L) 1.0 (0.99,1.01) 0.562
Serum total bilirubin(mg/dl) 0.48 (0.31,0.75) 0.001
Serum creatinine (mg/dl) 0.90 (0.68,1.20) 0.464
Uric acid (mg/dl) 0.74 (0.68,0.82) <0.001
BUN (mg/dl) 1.01 (0.99,1.02) 0.233
Serum sodium (mmol/L) 1.01 (0.98,1.05) 0.524
Serum phosphorus (mg/dl) 1.92 (1.58,2.33) <0.001
total calcium (mg/dl) 0.84 (0.63,1.13) 0.257
Serum potassium (mmol/L) 1.24 (0.93,1.64) 0.135
Serum iron (ug/dl) 1.0 (0.99,1.00) 0.064

Q, quartiles; OR, odds ratio; CI, confidence interval; * Other not defined by The NHANES but it does include multi-racial and non-Hispanic Asian; PIR, poverty-to-income ratio; CVD, Cardiovascular Disease; DM, diabetes mellitus; HbA1c, hemoglobin A1c; ALT, alanine transaminase; AST, alanine transaminase; BUN, blood urea nitrogen.