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. 2024 Dec 18;15:1496628. doi: 10.3389/fneur.2024.1496628

Table 2.

Comparison of laboratory parameters at different time points between good and poor outcome groups.

Variables Total
(n = 423)
Good outcome (n = 168) Poor outcome (n = 255) P-value
WBC day 0 8.53 (6.74, 10.98) 8.18 (6.65, 10.09) 8.80 (6.75, 11.94) 0.028
Neutrophils day 0 6.09 (4.36, 8.57) 5.45 (4.01, 7.42) 6.44 (4.58, 9.74) <0.001
Lymphocytes day 0 1.49 (1.04, 2.17) 1.75 (1.21, 2.42) 1.37 (0.94, 1.97) <0.001
Monocytes day 0 0.45 (0.35, 0.58) 0.43 (0.35, 0.58) 0.46 (0.35, 0.56) 0.898
NLR day 0 4.08 (2.34, 6.75) 3.11 (1.87, 4.90) 4.68 (2.74, 7.95) <0.001
dNLR day 0 2.85 (1.80, 4.70) 2.24 (1.43, 3.40) 3.31 (2.04, 5.51) <0.001
NMLR day 0 4.37 (2.60, 7.07) 3.40 (2.11, 5.14) 5.06 (3.01, 8.40) <0.001
WBC day 1 11.71 (9.80, 14.01) 10.58 (8.66, 12.57) 12.49 (10.34, 14.69) <0.001
Neutrophils day 1 9.99 (8.02, 12.03) 8.55 (6.91, 10.57) 10.73 (8.83, 12.93) <0.001
Lymphocytes day 1 1.05 (0.74, 1.38) 1.23 (0.92, 1.62) 0.93 (0.70, 1.21) <0.001
Monocytes day 1 0.60 (0.46, 0.74) 0.58 (0.46, 0.71) 0.61 (0.46, 0.79) 0.113
NLR day 1 9.68 (6.45, 13.90) 7.05 (5.05, 10.01) 11.66 (8.18, 17.12) <0.001
dNLR day 1 5.86 (4.23, 7.84) 4.66 (3.36, 6.12) 6.86 (4.99, 9.06) <0.001
NMLRay 1 10.29 (6.90, 14.79) 7.53 (5.46, 10.63) 12.38 (8.66, 17.88) <0.001
WBC day 3 10.62 (8.39, 13.66) 8.75 (7.05, 10.66) 12.13 (9.66, 15.60) <0.001
Neutrophils day 3 8.60 (6.39, 11.41) 6.38 (4.97, 8.24) 10.07 (8.11, 13.85) <0.001
Lymphocytes day 3 1.16 (0.86, 1.48) 1.37 (1.15, 1.69) 1.02 (0.73, 1.27) <0.001
Monocytes day 3 0.68 (0.49, 0.85) 0.61 (0.45, 0.77) 0.72 (0.54, 0.91) <0.001
NLR day 3 7.82 (4.80, 12.97) 5.00 (3.16, 6.58) 10.89 (7.61, 16.08) <0.001
dNLR day 3 4.50 (2.95, 6.65) 2.98 (2.16, 3.90) 5.84 (4.35, 7.77) <0.001
NMLR day 3 8.38 (5.19, 13.75) 5.46 (3.52, 7.10) 11.64 (8.19, 17.13) <0.001

Bold P-values indicate statistical significance (P < 0.05). WBC, white blood cell count; NLR, neutrophil-to-lymphocyte ratio; dNLR, derived neutrophil-to-lymphocyte ratio; NMLR, neutrophil-monocyte-to-lymphocyte ratio. Reference ranges: WBC 3.5–9.5 × 10^9/L, Neutrophils 1.8–6.3 × 10^9/L, Lymphocytes 1.1–3.2 × 10^9/L, Monocytes 0.10–0.60 × 10^9/L.