Table 2.
Odds of test completion Complete: N = 1,697 Incomplete/Ineligible: N = 133 |
Odds of completion and distance ≥ 200 m Complete, distance ≥ 200 m: N = 1,530 Incomplete/Ineligible/Distance < 200 m: N = 300 |
|||||||
---|---|---|---|---|---|---|---|---|
Simple adjusted1 | Fully adjusted2 | Simple adjusted1 | Fully adjusted2 | |||||
Characteristic (N = 1830) | aOR | 95% CI | aOR | 95% CI | aOR | 95% CI | aOR | 95% CI |
DPP treatment assignment (Ref: Placebo) | ||||||||
Lifestyle | 1.40 | 0.89, 2.21 | 1.49 | 0.87, 2.59 | 1.18 | 0.86, 1.63 | 1.09 | 0.76, 1.56 |
Metformin | 1.05 | 0.69, 1.59 | 0.86 | 0.53, 1.39 | 1.07 | 0.79, 1.45 | 0.94 | 0.66, 1.32 |
Baseline age group (Ref: 25–44 years) | ||||||||
45–59 years | 0.72 | 0.44, 1.14 | 0.72 | 0.41, 1.24 | 0.61 | 0.44, 0.85 | 0.61 | 0.41, 0.89 |
60+ years | 0.34 | 0.20, 0.59 | 0.30 | 0.14, 0.64 | 0.25 | 0.17, 0.38 | 0.28 | 0.17, 0.47 |
Sex (Male v. Female) | 0.88 | 0.60, 1.30 | 1.01 | 0.50, 2.05 | 1.05 | 0.79, 1.40 | 0.58 | 0.35, 0.94 |
Ethnicity (Ref: Non-Hispanic White) | ||||||||
Non-Hispanic Black | 0.69 | 0.44, 1.08 | 0.58 | 0.34, 1.00 | 0.63 | 0.46, 0.88 | 0.58 | 0.40, 0.85 |
Hispanic | 1.04 | 0.63, 1.78 | 0.89 | 0.48, 1.71 | 0.61 | 0.43, 0.87 | 0.66 | 0.43, 1.00 |
American Indian | 1.37 | 0.61, 3.67 | 1.44 | 0.53, 5.10 | 1.99 | 1.02, 4.37 | 2.49 | 1.15, 6.25 |
Asian | 1.17 | 0.49, 3.44 | 0.49 | 0.19, 1.54 | 0.82 | 0.45, 1.57 | 0.71 | 0.36, 1.52 |
Education (Less than College vs. College) | 0.53 | 0.36, 0.78 | 0.55 | 0.35, 0.86 | 0.56 | 0.42, 0.75 | 0.58 | 0.43, 0.80 |
Smoking (ref: Never)3 | ||||||||
Past | 0.78 | 0.53, 1.15 | 0.67 | 0.43, 1.04 | 0.83 | 0.64, 1.10 | 0.75 | 0.55, 1.02 |
Current | 0.40 | 0.18, 1.01 | 0.51 | 0.20, 1.63 | 0.60 | 0.31, 1.28 | 0.91 | 0.41, 2.28 |
BMI categories (ref: <30 kg/m2)3 | ||||||||
30–35 kg/m2 | 0.59 | 0.36, 0.97 | 0.56 | 0.30, 1.05 | 0.70 | 0.50, 0.98 | 0.86 | 0.57, 1.32 |
35–40 kg/m2 | 0.45 | 0.26, 0.77 | 0.60 | 0.26, 1.37 | 0.53 | 0.36, 0.77 | 0.82 | 0.48, 1.42 |
40+ kg/m2 | 0.21 | 0.12, 0.37 | 0.31 | 0.11, 0.84 | 0.29 | 0.19, 0.45 | 0.55 | 0.27, 1.12 |
Height (per 10 cm)3 | 0.97 | 0.73, 1.27 | 0.85 | 0.60, 1.19 | 1.29 | 1.06, 1.58 | 1.23 | 0.97, 1.55 |
Waist (per 15 cm)4 | 0.56 | 0.45, 0.68 | 0.79 | 0.55, 1.14 | 0.64 | 0.55, 0.74 | 0.80 | 0.62, 1.03 |
Grip strength (per 10 kg-force) 3 | 1.17 | 0.95, 1.48 | 1.16 | 0.91, 1.50 | 1.51 | 1.27, 1.80 | 1.45 | 1.20, 1.76 |
Median Physical Activity (per 5 MET-h/Wk)5 | 1.11 | 1.03, 1.22 | 1.03 | 0.94, 1.13 | 1.13 | 1.06, 1.20 | 1.09 | 1.02, 1.17 |
Neuropathy Signs/Symptoms (Present vs. Absent)3 | 0.50 | 0.33, 0.74 | 0.59 | 0.37, 0.92 | 0.42 | 0.31, 0.55 | 0.45 | 0.33, 0.61 |
Composite Health Issue (Present vs. Absent)6 | 0.41 | 0.28, 0.59 | 0.46 | 0.30, 0.70 | 0.56 | 0.43, 0.73 | 0.64 | 0.48, 0.87 |
Glycemic exposure (per 1% mean A1c)7 | 0.81 | 0.64, 1.04 | 0.98 | 0.74, 1.33 | 0.76 | 0.64, 0.91 | 0.91 | 0.74, 1.12 |
Bold font indicates a statistically significant association.
1Odds ratio adjusted for age group, sex, ethnicity, and education.
2Odds ratios adjusted for all other variables in the table; adjusted for treatment group, sex, and ethnicity.
3Collected at visit concurrent to 6MWT (year 15 visit).
4Collected 1 year prior to 6MWT (year 14 visit).
5Median of self-reported physical activity measures from DPP baseline through DPPOS Year 12.
6Includes recent hospitalization (past 12 months), history of hip replacement, history of stroke, CHF or MI, and recent falls (past 12 months).
7Mean HbA1c of all available measures DPP baseline through DPPOS Year 15.