Table 2.

HT vs NI Time-dependent Cox proportional hazards model on the outcome of a diagnosis of an eating disorder including Anorexia nervosa, Bulimia, Binge eating (analyzed as individual outcomes and as composite), among patients without any gender-affirming medical therapy (NI, reference group), to patients receiving hormone therapy (HT)

	Unweighted			Weighted
Model	HR	95% CI	p-Value	HR	95% CI	p-Value
Outcome: Eating disorder (composite)
Transfeminine	1.17	0.99, 1.38	0.06	1.67**	1.41, 1.98	<0.001
Transmasculine	0.57	0.53, 0.62	<0.001	0.83**	0.76, 0.90	<0.001
Outcome: Anorexia nervosa
Transfeminine	1.41	1.00, 1.97	0.047	1.94**	1.37, 2.74	<0.001
Transmasculine	0.51	0.43, 0.60	<0.001	0.73**	0.62, 0.86	<0.001
Outcome: Bulimia
Transfeminine	0.86	0.54, 1.37	0.525	1.18	0.73, 1.89	0.504
Transmasculine	0.66	0.51, 0.85	0.002	0.89	0.68, 1.17	0.423
Outcome: Binge eating
Transfeminine	1.45	0.84, 2.50	0.180	1.74	1.00, 3.02	0.051
Transmasculine	0.89	0.64, 1.23	0.471	1.13	0.81, 1.57	0.487

Result shown both before and after inverse probability treatment weighting.