Table 3.

SX vs NI

	Unweighted			Weighted
Model	HR	95% CI	p-Value	HR	95% CI	p-Value
Outcome: Eating disorder (composite)
Transfeminine	0.74	0.55, 1.00	0.047	1.31	0.91, 1.89	0.141
Transmasculine	0.37	0.31, 0.43	<0.001	0.62**	0.51, 0.75	<0.001
Outcome: Anorexia nervosa
Transfeminine	0.41	0.18, 0.95	0.037	1.23	0.46, 3.31	0.684
Transmasculine	0.3	0.21, 0.41	<0.001	0.44**	0.31, 0.63	<0.001
Outcome: Bulimia
Transfeminine	0.62	0.25, 1.57	0.315	1.14	0.43, 3.01	0.791
Transmasculine	0.55	0.35, 0.85	0.007	0.84	0.51, 1.38	0.496
Outcome: Binge eating
Transfeminine	1.01	0.41, 2.52	0.98	1.5	0.58, 3.90	0.402
Transmasculine	0.77	0.48, 1.25	0.296	1.01	0.59, 1.75	0.962

Time-dependent Cox proportional hazards model on the outcome of a diagnosis of an eating disorder including Anorexia nervosa, Bulimia, Binge eating (analyzed as individual outcomes and as composite), among patients without any gender-affirming medical therapy (NI; reference group), to patients receiving surgical intervention (SX). Result shown both before and after inverse probability treatment weighting.

** Significant.