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. 2024 Dec 31;17:398. doi: 10.1186/s13104-024-07050-w

Table 1.

Top 20 up- and down-regulated genes identified in DEG analysis. The table shows symbols of the genes, log 2FC, and description of top DEGs

Upregulated genes in LNCaP cell lines as compared to DU145 cell lines. Down-regulated genes in LNCaP cell lines as compared to DU145 cell lines
Symbols Log2 FC Description Symbols Log2 FC Description
SCN1A 8.03 sodium voltage-gated channel alpha subunit 1 HSPA6 -8.94 heat shock protein family A (Hsp70) member 6
MAP2K6 5.58 mitogen-activated protein kinase kinase 6 IL24 -6.39 interleukin 24
CP 5.15 ceruloplasmin NGFR -5.37 nerve growth factor receptor
ALDH3B2 5.07 aldehyde dehydrogenase 3 family member B2 NEURL3 -5.15 neuralized E3 ubiquitin protein ligase 3
BCO1 4.89 beta-carotene oxygenase 1 TMEM158 -5.07 transmembrane protein 158
FGB 4.76 fibrinogen beta chain HMGA2 -5.05 high mobility group AT-hook 2
MAML2 4.58 mastermind like transcriptional coactivator 2 COX6B2 -4.64 cytochrome c oxidase subunit 6B2
FGA 4.57 fibrinogen alpha chain PIK3CG -4.63 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
FGG 4.51 fibrinogen gamma chain DUSP15 -4.45 dual specificity phosphatase 15
CRLF1 4.44 cytokine receptor like factor 1 FOXS1 -4.45 forkhead box S1
SFTPB 4.36 surfactant protein B PLPP4 -4.33 phospholipid phosphatase 4
B3GNT7 4.33 UDP-GlcNAc: betaGal beta-1,3-N-acetylglucosaminyltransferase 7 U2AF1 -4.31 U2 small nuclear RNA auxiliary factor 1
FN1 4.21 fibronectin 1 TBX2 -4.30 T-box transcription factor 2
ST6GALNAC3 4.21 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 KCNMA1 -4.28 potassium calcium-activated channel subfamily M alpha 1
TET1 4.20 tet methylcytosine dioxygenase 1 HES7 -4.10 hes family bHLH transcription factor 7
FXYD2 4.18 FXYD domain containing ion transport regulator 2 HIGD2B -3.98 HIG1 hypoxia inducible domain family member 2B
FXYD6 4.18 FXYD domain containing ion transport regulator 6 CHST1 -3.97 carbohydrate sulfotransferase 1
FXYD6-FXYD2 4.18 FXYD6-FXYD2 readthrough MIOX -3.90 myo-inositol oxygenase
GPR68 4.10 G protein-coupled receptor 68 CCNA1 -3.86 cyclin A1
TGFB3 4.06 transforming growth factor beta 3 CHST8 -3.84 carbohydrate sulfotransferase 8