TABLE 3.
Viability assay results for A. nidulans wild-type and mutant strains
| Strain | % of colonies in presence of HU relative to untreated controlsa
|
|
|---|---|---|
| 6 mM | 100 mM | |
| GR5 (wild type) | 100.0 ± 0b | 100.0 ± 0b |
| AAH14 (ΔuvsB) | 74.6 ± 12.8 | 74.6 ± 10.3 |
| T20 (scaA::pyr-4) | 78.2 ± 8.1 | 70.0 ± 6.2 |
| GG11 (ΔuvsB scaA::pyr-4) | 84.8 ± 4.6 | 85.6 ± 11.2 |
a
Viability was determined as the percentage of colonies on HU-treated plates compared to those on untreated control plates. All results are averages of determinations from three independent experiments. The data are means ± standard deviations. Statistical differences were determined by one-way ANOVA followed, when significant, by the Newman-Keuls multiple comparison test, using Sigma Stat statistical software (Jandel Scientific). P < 0.05 was considered statistically significant.
b
Significantly different from all other treatments (P < 0.05).