TABLE 2.

Sensitivities, specificities, positive predictive values, and negative predictive values of HCII and PCR with and without reanalysis of discrepant samples

Clinical endpoint	Performance indicatora	HCII (%)	HCII with reanalysis (%)	PCR (%)	PCR with reanalysis (%)
Histopathology, CIN II+	Sensitivity	91.8	90.8	92.9	92.9
	Specificity	24.1	30.4	30.4	27.8
	PPV	60.0	61.8	62.3	61.5
	NPV	70.4	72.7	77.4	75.9
Histopathology, CIN III	Sensitivity	95.6	95.6	100.0	100.0
	Specificity	18.9	23.5	23.5	22.7
	PPV	28.7	29.9	30.8	30.6
	NPV	92.6	93.9	100.0	100.0
Cytology, CIN II+	Sensitivity	80.0	80.0	80.0	80.0
	Specificity	85.4	85.4	83.5	83.5
	PPV	21.1	21.1	19.0	19.0
	NPV	99.0	99.0	99.1	99.0
Cytology, CIN III	Sensitivity	100.0	100.0	100.0	100.0
	Specificity	84.0	84.0	82.1	82.1
	PPV	10.5	10.5	9.5	9.5
	NPV	100.0	100.0	100.0	100.0

^aPPV, positive predictive values; NPV, negative predictive values.