Table 3.

Differentiating cannabinoid hyperemesis syndrome from hyperemesis gravidarum.

Cannabinoid hyperemesis syndrome	Hyperemesis gravidarum
Severe cyclic nausea and vomiting Onset of symptoms at any gestational age Poor response to anti-emetic treatment Temporary relief of symptoms with hot bathing History of regular cannabis use Resolution with cannabis cessation Abdominal pain	Severe cyclic nausea and/or vomiting Onset of symptoms before 16 weeks’ gestation Usually responds to anti-emetic treatment