TABLE 4.
Summary of expression variations for genes associated with antimicrobial susceptibilitya
ORF | Gene name | LB LES400 ↑ vs PAO1 | H2O2 LES400 ↑ vs PAO1 | LB LES400 ↓ vs PAO1 | LB LES431 ↑ vs PAO1 | H2O2 LES431 ↑ vs PAO1 | LB LES431 ↓ vs PAO1 | H2O2 LES431 ↓vs PAO1 | LB LES431 ↑ vs 400 | H2O2 LES431 ↑ vs 400 | LB LES431 ↓ vs 400 | H2O2 LES431 ↓ vs 400 |
---|---|---|---|---|---|---|---|---|---|---|---|---|
PA0424 | mexR | 18 | 9.0 | 7.2 | 10 | |||||||
PA0425 | mexA | 3.4 | 2.6 | |||||||||
PA0426 | mexB | 2.4 | ||||||||||
PA0427 | oprM | 3.9 | 2.9 | |||||||||
PA0958 | oprD | 16 | 5.0 | 12 | ||||||||
PA2018 | mexY | 7.9 | 11 | |||||||||
PA2019 | mexX | 8.0 | 17 | 4.1 | 33 | |||||||
PA2020 | mexZ | 3.2 | ||||||||||
PA2493 | mexE | 16 | 66 | 18 | 295 | 5.1 | ||||||
PA2494 | mexF | 57 | ||||||||||
PA2495 | oprN | 6.0 | ||||||||||
PA4110 | ampC | 12 | 46 | 137 | 178 | 11 | 4.0 | |||||
PA4205 | mexG | 45 | 8.7 | 5.9 | ||||||||
PA4206 | mexH | 11 | 6.7 | 9.2 | ||||||||
PA4207 | mexI | 15 | 8.4 | 6.2 | 4.9 | |||||||
PA4208 | opmD | 4.3 | 8.0 | 5.5 | ||||||||
PA4599 | mexC | 28 | 10 | 32 | 43 | |||||||
PA4776 | pmrA | 6.7 | 6.6 | |||||||||
PA4777 | pmrB | 9.2 |
Arrows indicate isolates in which the gene is up-or down-regulated. LB or H2O2 indicate the two growth conditions used in this study. Values represent the average change in gene expression from replicate experiments.