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. 2025 Jan 2;6(1):e779. doi: 10.1002/mco2.779

FIGURE 4.

FIGURE 4

S protein‐specific IgG titers induced by CoV072 in mice. Serum was collected from mice 35 days after the primary immunization in the 5 µg two groups and 14 days after the primary immunization in the 15 µg single group. S protein‐specific IgG antibody titers against Omicron EG.5, Omicron XBB.1, Omicron BQ.1, and Omicron BA.4/5 variant were determined by ELISA. N = 5, geometric mean ± geometric standard deviation. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; ns: p > 0.05.