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. 2024 Dec 20;11:1418781. doi: 10.3389/fcvm.2024.1418781

Table 1.

Characteristics of postmenopausal CAD patients in the three groups divided by SIRI tertiles.

Variables Low level SIRI Intermediate level SIRI High level SIRI p-value
(SIRI <0.73) (1.29≥ SIRI <0.73) (SIRI ≥1.29)
SIRI
Age, years 63.98 ± 8.27 65.60 ± 8.42 67.75 ± 8.91 <0.001
WBC (×109/L) 5.22 ± 1.31 6.19 ± 1.35 8.31 ± 2.64 <0.001
Neut (×109/L) 2.86 ± 0.87 3.84 ± 0.88 6.17 ± 2.55 <0.001
Mono (×109/L) 0.34 ± 0.09 0.44 ± 0.11 0.55 ± 0.18 <0.001
Lymph (×109/L) 1.87 ± 0.62 1.73 ± 0.56 1.47 ± 0.53 <0.001
Hb (g/L) 122.72 ± 14.69 123.13 ± 13.33 121.35 ± 14.36 0.414
PLT (×109/L) 221.10 ± 60.98 225.54 ± 63.17 242.48 ± 73.79 0.003
TC (mmol/L) 4.17 ± 1.12 3.98 ± 0.96 4.02 ± 1.1 0.192
TG (mmol/L) 1.75 ± 1.43 1.84 ± 1.1 1.55 ± 0.88 0.038
HDL-C (mmol/L) 1.15 ± 0.28 1.09 ± 0.25 1.14 ± 0.27 0.048
LDL-C (mmol/L) 2.45 ± 0.97 2.31 ± 0.8 2.37 ± 0.95 0.281
Fib (g/L) 2.90 ± 0.52 3.15 ± 0.61 3.46 ± 0.98 <0.001
D-Dimer (mg/L) 0.25 ± 0.45 0.31 ± 0.68 0.45 ± 1.52 0.101
Cr (µmol/L) 63.09 ± 30.9 65.17 ± 20.04 70.88 ± 41.41 0.039
BUN (mmol/L) 5.52 ± 1.78 5.61 ± 1.91 6.84 ± 10.85 0.069
UA (µmol/L) 284.41 ± 81.81 295.62 ± 83.8 297.11 ± 99.59 0.285
ALT (U/L) 23.24 ± 21.29 28.74 ± 53.17 31.03 ± 43.07 0.149
AST (U/L) 29.06 ± 26.3 32.03 ± 43.07 53.95 ± 103.86 <0.001
TBIL (µmol/L) 9.14 ± 3.51 9.83 ± 5.41 10.06 ± 4.73 0.113
DBIL (µmol/L) 3.83 ± 1.6 4.13 ± 2.77 4.27 ± 2.23 0.128
IBIL (µmol/L) 5.25 ± 2.38 5.50 ± 2.94 5.75 ± 3.29 0.208
Alb (g/L) 41.89 ± 4.15 41.68 ± 3.42 40.07 ± 4.28 <0.001
FPG (mmol/L) 5.94 ± 2.5 6.40 ± 2.54 7.13 ± 3.57 <0.001
HbA1c (%) 6.43 ± 1.25 6.79 ± 1.32 6.70 ± 1.46 0.030
Hypertension (n,%) 138 (37.0) 147 (71.7) 147 (71.4) 0.508
Diabetes (n,%) 56 (27.2) 79 (38.5) 70 (34.0) 0.049
AF (n,%) 6 (2.9) 11 (5.4) 14 (5) 0.189
Number of lesions (n,%)
1-VD 58 (28.2) 43 (21.0) 28 (13.6) 0.001
2-VD 53 (25.7) 49 (23.9) 62 (30.1) 0.344
3-VD 95 (46.1) 114 (55.6) 117 (56.8) 0.059
LM 13 (6.3) 14 (6.8) 19 (9.2) 0.487
Medication use (n,%)
Antiplatelet drugs 206 (100) 205 (100) 206 (100) 1.000
Statins 206 (100) 205 (100) 206 (100) 1.000
β-blockers 68 (33.0) 57 (27.8) 50 (24.3) 0.141
ACEI or ARB 103 (50.0) 96 (46.8) 78 (37.9) 0.037

WBC, white blood cell; Neut, neutrophil; Mono, monocyte; Lymph, lymphocyte; Hb, hemoglobin; PLT, platelet; TG, triglycerides; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; Fib, fibrinogen; Cr, creatinine; BUN, blood urea nitrogen; UA, uric acid; ALT, alanine transaminase; AST, aspartate transaminase; TBIL, total bilirubin; DBIL, direct bilirubin; IBIL, indirect bilirubin; Alb, albumin; FPG, fasting blood glucose; HbA1c, glycosylated hemoglobin; AF, atrial fibrillation; LM, left main trunk lesion; ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotonin receptor blocker.