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. 2024 Dec 20;15:1528759. doi: 10.3389/fphar.2024.1528759

FIGURE 8.

FIGURE 8

AEA increases T-cell number through NR4A receptors in the AirPouch Zymosan model. Analysis of cellular infiltrate in murine AirPouch exudates after control (CTL) or AEA nanoformulation (AEA) pre-treatment (1 h) followed by zymosan stimulation (6 h) in mice inheriting a knockout for NR4A1−/− (A1KO), NR4A2−/− (A2KO) or double knockout for NR4A1/2−/−, compared to control mice (also shown in Figure 1). Mice without knockout on the floxed/cre background served as control (WT). Each data point represents an animal showing the total number of cells recovered by FACS analysis. 1-way ANOVA and Mann-Whitney test. n = 4–8. *p < 0.05.