Table 2.
Effects of UDCA and CDCA pretreatment on changes in BW, LW, and LW/BW in rats
| Parameters | Groups (mean ± SD) | |||||||
|---|---|---|---|---|---|---|---|---|
| C | LPS | UDCA | UDCA + LPS | CDCA | CDCA + LPS | |||
| BW (g) | 218.33 ± 7.20 | 212.00 ± 13.25 | 228.00 ± 13.61 | 207.50 ± 17.62 | 218.83 ± 16.95 | 206.00 ± 10.54 | ||
| LW (g) | 6.59 ± 0.32 | 10.92 ± 1.02†† | 6.43 ± 0.32 | 9.35 ± 1.42 | 6.00 ± 0.44 | 9.62 ± 0.53* | ||
| LW/BW | 0.030 ± 0.002 | 0.052 ± 0.003†† | 0.028 ± 0.001 | 0.045 ± 0.003* | 0.027 ± 0.002 | 0.047 ± 0.002* | ||
Data are expressed as the mean ± SD. BW- body weight; LW- liver weight; LW/BW- liver to body weight ratio; C- control group; LPS- LPS treated group; UDCA- Ursodeoxycholic acid treated group; UDCA + LPS- Ursodeoxycholic acid and LPS treated group; CDCA- Chenodeoxycholic acid treated group; CDCA + LPS- Chenodeoxycholic acid and LPS treated group. Mann-Whitney test and asterisk (*) indicate significant differences compared with LPS group * p < .05 and sign (†) indicate significant differences compared with C group † p < .05, †† p < .01