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. 2024 Aug 7;34(1):257–267. doi: 10.1007/s10068-024-01660-7

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — FS-Collagen peptide ameliorates UV- and d-gal-induced epidermal hyperplasia, and retains the component mass. (A) H&E staining of the skin tissue. (B) Masson staining of collagen fibrils. (C) Enlarged view of the collagen fibrils staining. (D) Transmission electron microscope imaging of skin tissue. (E) Relative collagen fibrils density. (F) Collagen I content in the skin tissue. (G) Hyaluronic acid content in the skin tissue. n = 5 in each group. ^#p < 0.05 compared to Ctrl; ^##p < 0.01 compared to Ctrl; *p < 0.05 compared to Mdl; **p < 0.01 compared to Mdl