Table 1.
Baseline characteristics of participants with metabolic associated fatty liver disease (MAFLD) stratified by body roundness index (BRI) and systemic immune-inflammation index (SII).
| Variables | Total | High SII and High BRI | High SII and Low BRI | Low SII and High BRI | Low SII and Low BRI | P value |
|---|---|---|---|---|---|---|
| Age | 49.24(0.23) | 50.56(0.39) | 47.64(0.39) | 52.21(0.43) | 47.28(0.34) | < 0.0001 |
| BRI | 6.29(0.03) | 8.10(0.05) | 4.88(0.02) | 7.73(0.05) | 4.79(0.02) | < 0.0001 |
| SII | 562.68(4.12) | 779.25(7.57) | 754.63(7.20) | 347.33(2.38) | 340.28(2.07) | < 0.0001 |
| Sex | < 0.0001 | |||||
| Female | 5850(44.69) | 2159(61.79) | 1169(39.29) | 1549(52.75) | 973(27.50) | |
| Male | 6585(55.31) | 1204(38.21) | 1720(60.71) | 1253(47.25) | 2408(72.50) | |
| eth1 | < 0.0001 | |||||
| Mexican American | 2556( 9.18) | 695( 8.77) | 588( 8.30) | 612(10.32) | 661( 9.55) | |
| Non-Hispanic Black | 2369(10.05) | 551( 9.19) | 366( 6.24) | 688(14.05) | 764(11.42) | |
| Non-Hispanic White | 5684(70.16) | 1687(71.78) | 1513(74.80) | 1126(66.64) | 1358(66.95) | |
| Other Hispanic | 1094( 5.68) | 300(6.11) | 233(5.48) | 256(4.95) | 305(6.01) | |
| Other Race - Including Multi-Racial | 732( 4.92) | 130(4.14) | 189(5.19) | 120(4.05) | 293(6.06) | |
| Edu | < 0.0001 | |||||
| Above high school | 5863(55.72) | 1523(53.46) | 1388(55.43) | 1240(53.89) | 1712(59.48) | |
| High school or equivalent | 2973(25.60) | 800(26.11) | 749(27.83) | 648(24.67) | 776(23.74) | |
| Under high school | 3599(18.68) | 1040(20.43) | 752(16.74) | 914(21.44) | 893(16.78) | |
| Family_income | < 0.0001 | |||||
| High | 3775(41.90) | 879(37.39) | 997(45.64) | 711(37.47) | 1188(46.00) | |
| Low | 3753(20.52) | 1151(24.14) | 784(18.15) | 970(23.90) | 848(16.79) | |
| Medium | 4907(37.58) | 1333(38.47) | 1108(36.21) | 1121(38.62) | 1345(37.21) | |
| Marital | < 0.0001 | |||||
| Married | 8045(68.33) | 2053(64.83) | 1923(69.08) | 1718(65.95) | 2351(72.72) | |
| Other | 4390(31.67) | 1310(35.17) | 966(30.92) | 1084(34.05) | 1030(27.28) | |
| BMI | < 0.0001 | |||||
| <23.9 | 385( 2.78) | 4(0.06) | 183(5.20) | 0(0.00) | 198(5.19) | |
| >=28 | 8994(73.20) | 3190(96.72) | 1389(51.73) | 2689(96.74) | 1726(53.29) | |
| 24 ~ 27.9 | 3056(24.02) | 169( 3.22) | 1317(43.07) | 113( 3.26) | 1457(41.51) | |
| Alcohol.user | < 0.0001 | |||||
| Former | 2544(17.59) | 799(21.56) | 509(15.26) | 673(20.97) | 563(13.47) | |
| Heavy | 2528(20.84) | 590(17.89) | 681(23.97) | 485(17.02) | 772(23.59) | |
| Mild | 4000(35.45) | 984(32.34) | 976(36.65) | 824(33.11) | 1216(39.00) | |
| Moderate | 1648(15.10) | 427(14.58) | 406(15.58) | 363(15.62) | 452(14.77) | |
| Never | 1715(11.03) | 563(13.64) | 317( 8.54) | 457(13.27) | 378( 9.17) | |
| Smoke | < 0.0001 | |||||
| Former | 3569(29.00) | 994(30.76) | 805(27.73) | 810(29.70) | 960(27.99) | |
| Never | 6392(50.64) | 1746(49.93) | 1370(47.29) | 1536(53.89) | 1740(51.99) | |
| Now | 2474(20.36) | 623(19.30) | 714(24.98) | 456(16.41) | 681(20.02) | |
| Hypertension | < 0.0001 | |||||
| No | 6246(53.66) | 1426(43.14) | 1672(61.77) | 1162(45.77) | 1986(61.99) | |
| Yes | 6189(46.34) | 1937(56.86) | 1217(38.23) | 1640(54.23) | 1395(38.01) | |
| DM | < 0.0001 | |||||
| No | 9437(80.72) | 2325(72.43) | 2418(87.68) | 1874(72.55) | 2820(88.19) | |
| Yes | 2998(19.28) | 1038(27.57) | 471(12.32) | 928(27.45) | 561(11.81) | |
| Hyperlipidemia | 0.04 | |||||
| No | 2033(16.79) | 507(15.72) | 450(15.92) | 450(16.38) | 626(18.89) | |
| Yes | 10,402(83.21) | 2856(84.28) | 2439(84.08) | 2352(83.62) | 2755(81.11) | |
| CVD | < 0.0001 | |||||
| No | 10,867(89.49) | 2852(86.77) | 2580(91.56) | 2363(86.28) | 3072(92.53) | |
| Yes | 1567(10.51) | 511(13.23) | 309( 8.44) | 438(13.72) | 309( 7.47) | |
| Mortstat | < 0.0001 | |||||
| 0 | 10,452(88.01) | 2724(85.21) | 2397(87.53) | 2340(87.46) | 2991(91.49) | |
| 1 | 1983(11.99) | 639(14.79) | 492(12.47) | 462(12.54) | 390( 8.51) | |