Table 3.
Significant factors associated with mortality in all patients.
| Variable | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95%CI) | p-value | HR (95%CI) | p-value | |
| Decompensated cirrhosis | 7.291 (3.918–13.569) | < 0.001 | 6.079 (3.134–11.795) | < 0.001 |
| Child–Pugh score | 1.528 (1.335–1.750) | < 0.001 | ||
| MELD score | 1.194 (1.107–1.287) | < 0.001 | ||
| Total bilirubin (mg/dL) | 1.453 (1.236–1.708) | < 0.001 | 1.251 (1.043–1.502) | 0.016 |
| Albumin (g/dL) | 0.251 (0.159–0.396) | < 0.001 | ||
| Prothrombin time (%) | 0.978 (0.964–0.993) | 0.004 | ||
| M2BPGi (C.O.I.) | 1.138 (1.071–1.210) | < 0.001 | ||
| Osteoporosis | 1.894 (1.086–3.305) | 0.024 | ||
| Frailty | 4.520 (2.511–8.137) | < 0.001 | 3.564 (1.918–6.625) | < 0.001 |
| Fracture | 3.037 (1.713–5.384) | < 0.001 | 2.470 (1.365–4.472) | 0.003 |
| HCC | 2.642 (1.403–4.974) | 0.003 | 3.274 (1.676–6.394) | < 0.001 |
CI, confidence interval; C.O.I., cut-off index; HCC, hepatocellular carcinoma; HR, hazard ratio; M2BPGi, Mac-2 binding protein glycosylation isomer; MELD, model for end-stage liver disease.