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. 2025 Jan 2;15:95. doi: 10.1038/s41598-024-83862-x

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Distributions of TIL^(Basic) and its day-to-day changes in the study population. (a) Alluvial diagram of the evolution of the TIL^(Basic) distribution in the study population over the assessed days of ICU stay. Percentages which round to 2% or lower are not shown. (b) Distributions of day-to-day changes in TIL^(Basic). The numbers above each bar represent the number of study patients remaining in the ICU after the corresponding day-to-day step. Percentages which round to 2% or lower are not shown. Abbreviations: ICU = intensive care unit, TIL = therapy intensity level, TIL^(Basic) = condensed, five-category TIL scale as defined in Table 1, WLST = withdrawal of life-sustaining therapies.