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. 2025 Jan 2;15:4. doi: 10.1038/s41598-024-84077-w

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 1 — Outcome of the IMM cases. (A) Outcome of IMM Case 1, (B) Outcome of IMM Case 2. *Steroids were administered as part of gene therapy treatment. BID twice daily, BiPAP bilevel positive airway pressure, BNP brain natriuretic peptide, BUN blood urea nitrogen, CK creatine kinase, cMRI cardiac magnetic resonance imaging, CXR chest X-ray, ECG electrocardiogram, ECHO echocardiogram, EDVi end-diastolic volume, ELISpot enzyme-linked immunosorbent spot, ESR erythrocyte sedimentation rate, Hct hematocrit, Hg hemoglobin, IMM immune-mediated myositis, INR international normalized ratio, IVIG intravenous immunoglobulin, LFT liver function test, MRI magnetic resonance imaging, NG nasogastric tube, NSAA North Star Ambulatory Assessment, PTT partial thromboplastin time, Strep Streptococcus pyogenes, WBC white blood cell.