Table 5.
Short-term complications | Mortality | Short-term mortality after acute PE might be decreasing. |
Recurrent VTE | Recurrent VTE is very infrequent while receiving standard anticoagulation. If confirmed, consider malignancy or antiphospholipid syndrome. | |
Atrial fibrillation | Newly diagnosed AF might worsen the prognosis of patients with PE. | |
Long-term complications | Mortality | It is increased in patients with PE, compared to the general population. Cancer accounts for the vast majority of the deaths in patients who survive the acute phase. |
Recurrent VTE | Current guidelines provide general recommendations for the duration of anticoagulation after an episode of PE. | |
Dyspnea | Persistent dyspnea is common after treatment of PE. | |
CTED | CTED indicates a limitation in exercise capacity, consistent with pulmonary vascular disease, but in the absence of elevated pulmonary arterial pressures. | |
CTEPH | Diagnosis and management of CTEPH requires particular expertise and should be done in referral centers of excellence. Treatment options may include drug therapy, balloon pulmonary angioplasty, and pulmonary thromboendarterectomy. |
PE, pulmonary embolism; VTE, venous thromboembolism; AF, atrial fibrillation; CTED, chronic thromboembolic disease; CTEPH, chronic thromboembolic pulmonary hypertension.