Table 3.
Signals related to age differences.
| Child-specific signals | Elderly specific signals | ||||
|---|---|---|---|---|---|
| Adverse event | Frequency | Signal risk ratio | Adverse event | Frequency | Signal risk ratio |
| Vomiting a | 89 | 2.79 | Gout b | 32 | 7.85 |
| Drug hypersensitivity a | 15 | 2.4 | Pancytopenia b | 47 | 3.71 |
| Dyspnea | 36 | 2.32 | Hyperkalemia b | 36 | 2.95 |
| Chromaturia | 29 | 2.86 | |||
| Bradycardia b | 41 | 2.55 | |||
| Drug resistance | 26 | 2.43 | |||
| Drug interaction | 487 | 2.38 | |||
| Torsade de pointes | 32 | 2.36 | |||
| Rhabdomyolysis | 68 | 2.25 | |||
| Electrocardiogram QT prolonged | 58 | 2.22 | |||
| Muscular weakness b | 41 | 2.07 | |||
| Hyperhidrosis b | 35 | 2.04 | |||
| Hypoglycemia | 60 | 1.97 | |||
| Oral pain | 23 | 1.88 | |||
| Renal failure acute | 85 | 1.76 | |||
a
Signals generated by children rather than signals not generated by children.
b
Signals generated by elderly individuals rather than signals not generated by elderly individuals.