Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2025 Jan 2;24:2. doi: 10.1186/s12943-024-02182-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — Identification of WNT signalling as a key driver of communication networks in metastatic cells. A Total cell–cell interactions across different cell types in samples with high metastatic potential. B Comparison of the number of interactions between metastatic high and metastatic medium scored cells. C WNT signalling interactions among cell types in metastatic medium scored cells. D WNT signalling interactions among cell types in metastatic high scored cells. E Communication networks mediated by WNT signalling in metastatic medium scored cells. F Communication networks mediated by WNT signalling in metastatic high scored cells. G Top ligand interactions driving WNT signalling in metastatic high cells. (H) UCell scoring of WNT target genes across metastatic timepoints, highlighting gradual increases in expression and the implication of WNT signalling in metastatic cells