Table 4.
Trials of SLNB omission
| Design | Age | Stage | ER/PR status | Breast radiotherapy | Results | ||
|---|---|---|---|---|---|---|---|
| SOUND [30] | RCT | SLNB Vs. no SLNB | any | cT1N0 (US) | any | yes | 5y DFS 97.7% Vs. 98% |
| INSEMA [31] | RCT | SLNB vs. no SLNB | ≥ 18 | cT1-2N0 | any | yes | Not recruiting |
| NAUTILUS [33] | RCT | SLNB vs. no SLNB | ≥ 19 | cT1-2N0 (US) | any | yes | recruiting |
| BOOG 2013–08 [34] | RCT | SLNB vs. no SLNB | ≥ 18 | cT1-2N0 (PE + US) | any | Yes | recruiting |
| SOAPET (https://classic.clinicaltrials.gov/show/NCT04072653) | Single group | no SLNB | ≥ 18 |
cT1-2N0 (PE + US. LymphPET) |
any | Yes | recruiting |