Table 4.

Results of linear mixed model comparing controls and cancer survivors for primary and secondary outcomes, unadjusted and adjusted analyses

	Unadjusted model		Adjusted model
	RC (95% CI)	p value	RC (95% CI)	p value
SPPB summary score (n = 382)
Control—ref. Survivor	0 –0.31 (–0.71; 0.09)	0.132	0 –0.38 (–0.77; 0.01)	0.057
Cohabitant status, living with others a Comorbidities a	0.78 (0.22; 1.35) –0.11 (–0.22; –0.007)	0.006 0.037	0.78 (0.21; 1.35) –0.11 (–0.22; –0.01)	0.007 0.033
Grip strength (kg; n = 381)
Control—ref. Survivor	0 –5.47 (–7.06; –3.88)	<0.001	0 –5.81 (–7.46; –4.17)	<0.001 *
Cohabitant status, living with others a Comorbidities a	1.06 (–1.00; 3.12) –0.75 (–1.31; –0.18)	0.312 0.009	1.17 (–0.88; 3.21) –0.76 (–1.32; –0.21)	0.264 0.007
One-legged balance (s; n = 372)
Control—ref. Survivor	0 –3.49 (–5.86; –1.13)	0.004	0 –4.36 (–6.72; –2.00)	<0.001 *
Cohabitant status, living with others a Comorbidities a	2.97 (–0.02; 5.96) –1.49 (–2.15; –0.83)	0.051 <0.001	3.03 (0.01; 6.05) –1.50 (–2.14; –0.86)	0.049 <0.001
Gait speed (m/s; n = 382)
Control—ref. Survivor	0 –0.02 (–0.07; 0.02)	0.284	0 –0.04 (–0.08; 0.008)	0.106
Cohabitant status, living with others a Comorbidities a	0.10 (0.04; 0.16) –0.02 (–0.03; –0.007)	0.001 0.003	0.10 (0.04; 0.16) –0.02 (–0.03; –0.008)	0.002 0.002
Physical Activity Index (n = 375)
Control—ref. Survivor	0 –0.05 (–0.66; 0.56)	0.867	0 –0.14 (–0.75; 0.47)	0.648
Cohabitant status, living with others a Comorbidities a	0.48 (–0.26; 1.22) –0.15 (–0.36; 0.06)	0.205 0.165	0.49 (–0.26; 1.25) –0.15 (–0.36; 0.06)	0.198 0.161

CI = confidence interval; RC = regression coefficient; ref. = reference; SPPB = Short Physical Performance Battery.

Due to missing values on several confounders, the number of survivors and controls with results available for analysis (n) was lower than expected.

^*Significance level p < 0.05.

^aPair (control vs case) variable is present in these models.