Figure 1.

CONSORT Diagram.

Of 32 participants screened, 5 did not meet the screening criteria, and the remaining 27 patients were randomly assigned. Before leukapheresis, two participants randomly assigned to placebo withdrew consent. Sixteen participants in the AVT001 group and nine participants in the placebo group received study treatment as planned and completed the follow-up visits through day 150. One participant withdrew from the study before the visit on day 360. AutoAb neg denotes autoantibody negative.