Table 1.
The disease burden of CVD and subtypes caused by kidney dysfunction among 25–64 years in globally and China in 1992 and 2021
| Deaths (95% UI) | DALYs (95% UI) | ASMR (95% UI, per 105 population) | ASDR (95% UI, per 105 population) | EAPC (95% Cl) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1992 | 2021 | 1992 | 2021 | 1992 | 2021 | 1992 | 2021 | ASMR | ASDR | |||
| Global | CVD | Both |
309,007 (245954 to 388446) |
421,366 (326601 to 543732) |
11,542,853 (9170832 to 14534095) |
15,889,762 (12313170 to 20472002) |
14.66 (11.68 to 18.41) |
10.37 (8.03 to 13.39) |
542.21 (431.50 to 681.78) |
392.70 (304.04 to 506.26) |
-1.32 (-1.37 to -1.27) |
-1.23 (-1.27 to -1.18) |
| Female |
114,135 (90910 to 142901) |
143,476 (111157 to 184298) |
4,294,947 (3410445 to 5385860) |
5,468,810 (4233187 to 6994877) |
10.83 (8.63 to 13.54) |
6.96 (5.39 to 8.95) |
404.25 (321.44 to 506.14) |
267.32 (206.69 to 342.19) |
-1.68 (-1.78 to -1.59) |
-1.57 (-1.65 to -1.49) |
||
| Male |
194,871 (153217 to 246965) |
277,890 (213242 to 361655) |
7,247,906 (5700619 to 9224985) |
10,420,952 (8010470 to 13581368) |
18.48 (14.55 to 23.4) |
13.85 (10.62 to 18.03) |
679.15 (535.12 to 862.98) |
520.28 (399.65 to 678.25) |
-1.10 (-1.14 to -1.05) |
-1.01 (-1.06 to -0.97) |
||
| IHD | Both |
176,973 (126311 to 237219) |
261,842 (184076 to 356830) |
6,519,033 (4641976 to 8782893) |
9,657,652 (6768890 to 13220680) |
8.37 (5.98 to 11.21) |
6.45 (4.54 to 8.80) |
304.83 (217.26 to 410.29) |
239.22 (167.59 to 327.55) |
-1.01 (-1.07 to -0.96) |
-0.95 (-1.00 to -0.90) |
|
| Female |
57,256 (40760 to 76430) |
80,688 (55888 to 109415) |
2,091,624 (1483865 to 2804748) |
2,945,453 (2028395 to 4016679) |
5.41 (3.85 to 7.21) |
3.93 (2.72 to 5.33) |
195.85 (139.12 to 262.21) |
144.41 (99.39 to 197.05) |
-1.24 (-1.34 to -1.13) |
-1.17 (-1.27 to -1.07) |
||
| Male |
119,717 (85425 to 162061) |
181,154 (126854 to 248553) |
4,427,409 (3153265 to 6021082) |
6,712,199 (4687964 to 9235448) |
11.31 (8.08 to 15.3) |
9.04 (6.33 to 12.4) |
412.80 (294.29 to 560.76) |
335.52 (234.24 to 461.68) |
-0.88 (-0.93 to -0.84) |
-0.82 (-0.87 to -0.77) |
||
| Stroke | Both |
130,856 (99771 to 169308) |
157,849 (118238 to 204533) |
4,973,381 (3763795 to 6430175) |
6,156,706 (4571846 to 8010140) |
6.24 (4.76 to 8.06) |
3.87 (2.90 to 5.02) |
234.96 (178.16 to 303.30) |
151.64 (112.51 to 197.49) |
-1.77 (-1.83 to -1.71) |
-1.62 (-1.68 to -1.56) |
|
| Female |
56,578 (43193 to 72304) |
62,269 (46203 to 81259) |
2,185,833 (1658828 to 2803309) |
2,493,354 (1834850 to 3256502) |
5.39 (4.12 to 6.88) |
3.01 (2.23 to 3.93) |
206.72 (157.21 to 264.71) |
121.46 (89.28 to 158.83) |
-2.20 (-2.29 to -2.10) |
-2.00 (-2.09 to -1.92) |
||
| Male |
74,278 (56056 to 96937) |
95,581 (71296 to 124515) |
2,787,548 (2092053 to 3636259) |
3,663,352 (2720661 to 4781964) |
7.09 (5.36 to 9.24) |
4.76 (3.55 to 6.20) |
263.16 (197.91 to 342.72) |
182.49 (135.48 to 238.39) |
-1.46 (-1.51 to -1.41) |
-1.33 (-1.39 to -1.28) |
||
| LEPAD | Both |
1177 (788 to 1620) |
1674 (1135 to 2300) |
50,438 (32221 to 70871) |
75,405 (48182 to 109780) |
0.06 (0.04 to 0.08) |
0.04 (0.03 to 0.06) |
2.43 (1.55 to 3.41) |
1.84 (1.18 to 2.69) |
-1.57 (-1.75 to -1.39) |
-1.30 (-1.43 to -1.17) |
|
| Female |
301 (206 to 411) |
520 (345 to 719) |
17,490 (10816 to 27085) |
30,003 (18479 to 46525) |
0.03 (0.02 to 0.04) |
0.02 (0.02 to 0.03) |
1.67 (1.04 to 2.59) |
1.44 (0.89 to 2.23) |
-0.94 (-1.12 to -0.75) |
-0.77 (-0.87 to -0.67) |
||
| Male |
876 (582 to 1213) |
1155 (782 to 1609) |
32,948 (21235 to 45670) |
45,402 (29392 to 64092) |
0.08 (0.06 to 0.12) |
0.06 (0.04 to 0.08) |
3.19 (2.05 to 4.42) |
2.26 (1.46 to 3.19) |
-1.78 (-1.96 to -1.59) |
-1.57 (-1.72 to -1.42) |
||
| China | CVD | Both |
54,551 (41704 to 71173) |
60,454 (43532 to 82810) |
2,063,479 (1576334 to 2682673) |
2,319,803 (1688845 to 3158839) |
11.28 (8.63 to 14.7) |
6.14 (4.41 to 8.43) |
420.07 (321.25 to 545.38) |
239.19 (173.85 to 326.59) |
-1.82 (-2.04 to -1.59) |
-1.68 (-1.89 to -1.46) |
| Female |
23,873 (17662 to 32216) |
20,576 (14249 to 29551) |
904,995 (671721 to 1212350) |
803,700 (565144 to 1138842) |
10.36 (7.67 to 13.96) |
4.16 (2.88 to 5.99) |
386.97 (287.68 to 517.87) |
164.91 (115.79 to 233.95) |
-2.98 (-3.24 to -2.73) |
-2.80 (-3.03 to -2.57) |
||
| Male |
30,678 (22821 to 41314) |
39,879 (27541 to 57215) |
1,158,483 (862416 to 1555132) |
1,516,103 (1055688 to 2162210) |
12.12 (9.02 to 16.31) |
8.07 (5.57 to 11.6) |
450.36 (335.51 to 603.75) |
311.55 (216.67 to 445.48) |
-1.04 (-1.28 to -0.80) |
-0.92 (-1.14 to -0.69) |
||
| IHD | Both |
18,186 (12425 to 25798) |
26,133 (16061 to 39462) |
695,470 (474300 to 987319) |
968,125 (596430 to 1460928) |
3.70 (2.53 to 5.24) |
2.69 (1.66 to 4.07) |
138.53 (94.57 to 196.46) |
101.85 (62.79 to 153.83) |
-0.61 (-0.87 to -0.35) |
-0.61 (-0.86 to -0.37) |
|
| Female |
7755 (5167 to 11113) |
8224 (4824 to 12602) |
290,783 (194495 to 416797) |
297,271 (174337 to 456884) |
3.31 (2.21 to 4.74) |
1.69 (0.99 to 2.59) |
121.97 (81.65 to 174.34) |
62.04 (36.31 to 95.46) |
-1.94 (-2.20 to -1.68) |
-1.98 (-2.22 to -1.73) |
||
| Male |
10,431 (6919 to 15359) |
17,908 (10714 to 28158) |
404,687 (267838 to 593083) |
670,854 (402809 to 1047843) |
4.05 (2.69 to 5.96) |
3.67 (2.20 to 5.78) |
153.67 (101.79 to 225.35) |
140.49 (84.51 to 219.46) |
0.21 (-0.07 to 0.49) |
0.20 (-0.06 to 0.47) |
||
| Stroke | Both |
36,335 (26451 to 49299) |
34,268 (23988 to 47804) |
1,364,083 (994085 to 1844872) |
1,345,141 (946559 to 1854558) |
7.58 (5.52 to 10.27) |
3.44 (2.41 to 4.81) |
280.71 (204.97 to 379.06) |
136.7 (96.00 to 189.22) |
-2.56 (-2.79 to -2.32) |
-2.32 (-2.54 to -2.10) |
|
| Female |
16,105 (11227 to 22870) |
12,331 (8312 to 17817) |
611,661 (431020 to 859417) |
502,375 (344031 to 712207) |
7.04 (4.91 to 9.98) |
2.47 (1.66 to 3.57) |
263.88 (186.33 to 370.46) |
102.05 (69.72 to 144.99) |
-3.58 (-3.85 to -3.30) |
-3.25 (-3.48 to -3.01) |
||
| Male |
20,230 (14338 to 28296) |
21,937 (14725 to 31598) |
752,422 (533837 to 1050840) |
842,766 (570014 to 1201798) |
8.07 (5.73 to 11.28) |
4.39 (2.95 to 6.33) |
296.14 (210.47 to 413.26) |
170.56 (115.23 to 244.04) |
-1.84 (-2.08 to -1.60) |
-1.65 (-1.87 to -1.43) |
||
| LEPAD | Both |
30 (19 to 46) |
53 (32 to 83) |
3926 (2040 to 7374) |
6537 (3197 to 12046) |
0.01 (0 to 0.01) |
0.01 (0 to 0.01) |
0.83 (0.43 to 1.56) |
0.65 (0.32 to 1.20) |
-0.41 (-0.55 to -0.27) |
-0.67 (-0.83 to -0.51) |
|
| Female |
13 (8 to 21) |
20 (11 to 32) |
2552 (1246 to 5000) |
4054 (1780 to 7797) |
0.01 (0 to 0.01) |
0 (0 to 0.01) |
1.13 (0.55 to 2.21) |
0.81 (0.36 to 1.56) |
-1.54 (-1.71 to -1.36) |
-1.11 (-1.26 to -0.96) |
||
| Male |
17 (10 to 27) |
34 (19 to 56) |
1374 (756 to 2400) |
2483 (1307 to 4367) |
0.01 (0 to 0.01) |
0.01 (0 to 0.01) |
0.56 (0.31 to 0.97) |
0.49 (0.26 to 0.87) |
0.41 (0.17 to 0.65) |
-0.04 (-0.24 to 0.16) |
||
ASMR, age-standardized mortality rates; ASDR, age-standardized disability-adjusted life years rates; EAPC, estimated annual percentage change; CVD, cardiovascular diseases; IHD, ischemic heart disease; LEPAD, lower extremity peripheral arterial disease; CI, confidence intervals; UI, uncertainty intervals