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. 2025 Jan 3;20(1):e0316934. doi: 10.1371/journal.pone.0316934

Table 1. The baseline characteristics of participants.

Variables Total (582) T1(≤0.28, 194) T2 (0.28 -≤0.42, 194) T3 (>0.42, 194) P value
Age, years 32.07 ± 3.78 31.56 ± 3.57 32.48 ± 3.56 32.17 ± 4.14 0.050
Pre-pregnancy BMI (kg/m2) 22.03 ± 3.49 21.24 ± 2.98 22.09 ± 3.53 22.78 ± 3.76 < 0.001
Parity, n (%) 0.082
No 304 (52.23) 114 (58.76) 94 (48.45) 96 (49.48)
Yes 278 (47.77) 80 (41.24) 100 (51.55) 98 (50.52)
Hepatic steatosis, n (%) < 0.001
Grade 0 472 (81.10) 170 (87.63) 167 (86.08) 135 (69.59)
Grade 1 85 (14.60) 23 (11.86) 21 (10.82) 41 (21.13)
Grade 2 17 (2.92) 1 (0.52) 4 (2.06) 12 (6.19)
Grade 3 8 (1.37) 0 (0) 2 (1.03) 6 (3.09)
AST (IU/L) 16.00 (14.00, 20.00) 16.00 (14.00, 18.75) 16.00 (14.00, 19.00) 17.00 (14.00, 21.00) 0.162
ALT (IU/L) 11.00 (8.00, 15.00) 11.00 (8.00, 13.75) 11.00 (8.00, 15.00) 12.00 (8.00, 18.00) 0.098
GGT(IU/L) 12.00 (10.00, 15.00) 11.00 (10.00, 14.00) 12.00 (10.00, 15.00) 13.00 (10.00, 17.00) 0.002
Adipokines(ng/mL) 5026.25 (2821.33, 8051.02) 6588.00 (3778.50, 10005.25) 5331.05 (3310.75, 8236.70) 3278.60 (1941.53, 6069.62) < 0.001
TC (mg/dL) 172.85 ± 27.04 171.51 ± 26.67 171.78 ± 26.27 175.27 ± 28.12 0.312
TG (mg/dL) 119.00 ± 47.56 81.96 ± 19.14 110.70 ± 21.63 164.34 ± 49.60 < 0.001
HDL-C(mg/dL) 65.02 ± 13.35 74.08 ± 11.82 64.92 ± 10.91 56.05 ± 10.68 < 0.001
LDL-C(mg/dL) 84.04 ± 21.62 81.05 ± 21.04 84.72 ± 20.08 86.35 ± 23.38 0.047
FPG (mg/dL) 76.88 ± 9.66 76.78 ± 10.11 76.73 ± 8.62 77.12 ± 10.22 0.909
Insulin (μIU/mL) 8.40 (5.32, 11.57) 6.40 (4.30, 9.47) 7.90 (5.50, 10.88) 10.65 (7.43, 15.30) < 0.001
HOMA-IR 1.50 (1.00, 2.30) 1.20 (0.80, 1.87) 1.50 (1.00, 2.20) 2.00 (1.40, 2.88) < 0.001
RC (mg/dL) 23.80 ± 9.52 16.38 ± 3.81 22.14 ± 4.33 32.87 ± 9.92 < 0.001
RC/HDL-C ratio 0.33 (0.26, 0.47) 0.23 (0.19, 0.26) 0.33 (0.31, 0.37) 0.54 (0.47, 0.66) < 0.001

Continuous variables are presented as mean (standard deviation) or medians (interquartile range), while categorical variables are expressed as percentages (%).

RC remnant cholesterol, BMI body mass index, ALT alanine aminotransferase, AST aspartate aminotransferase, GGT gamma-glutamyl transferase, HDL-C high-density lipoprotein cholesterol, TC total cholesterol, TG triglycerides, LDL-C low-density lipid cholesterol, FPG fasting plasma glucose, HOMA-IR homeostasis model assessment-insulin resistance.