Table 3.

Optical coherence tomography (OCT) measurements of enrolled eyes: differences between healthy eyes and dementia with Lewy Bodies (DLB) eyes

OCT measurements (mean ± SD or median and IQR)	Total (n = 66)	Control eyes (n = 36)	DLB eyes (n = 30)	p-value
CMT, µm	271 (257; 286)	284.5 (262; 290)	263.5 (252; 271)	< 0.001†
NFL, µm (1 mm)	13.1 ± 2.0	13.4 ± 2.2	12.8 ± 1.7	0.185*
NFL, µm (3 mm)	23.0 ± 2.7	23.7 ± 2.9	22.3 ± 2.2	0.036*
GCL + IPL, µm (1 mm)	34.8 ± 6.2	36.8 ± 7.2	32.3 ± 3.6	0.003*
GCL + IPL, µm (3 mm)	83.8 ± 11.6	87.5 ± 8.5	79.2 ± 13.2	0.003*
INL, µm	22.7 ± 6.3	22.4 ± 6.0	23.0 ± 6.7	0.681*
OPL, µm	26.5 (25; 31)	29 (25; 31.5)	26 (25; 29)	0.067†
ONL, µm	87.9 ± 9.6	89.9 ± 9.6	85.6 ± 9.1	0.070*
RPE, µm	16.7 ± 2.3	17.1 ± 2.3	16.1 ± 2.2	0.074*
IRL, µm	183.1 ± 19.8	190.1 ± 20.0	174.8 ± 16.1	0.001*
ORL, µm	86.5 ± 5.5	86.8 ± 6.1	86.2 ± 4.7	0.643*

*Unpaired t-test, †Mann-Whitney U test

P-values < 0.05 are given in bold-italic entries

CMT: Central Macular Thickness; NFL: Nerve Fiber Layer; GCL-IPL: Ganglion Cell Layer-Inner Plexiform Layer complex: INL: Inner Nuclear Layer, OPL: Outer Plexiform Layer, ONL: Outer Nuclear Layer, RPE: Retinal Pigment epithelium, IRL: Inner Retinal Layer, ORL: Outer Retinal Layer