Table 5.
Comparison of median values of fold change of studied miRNA -101 as marker for differentiating HCC group from cirrhotic groups
| Denotation | miRNA-101 FC (2-ΔCT) | P. Value ANOVA | P value (unpaired t-test) | ||||
|---|---|---|---|---|---|---|---|
| Control (n = 20) | HCC (n = 40) | Cirrhotic (n = 40) |
HCC vs HC | Cirrhotic vs HC | HCC vs Cirrhotic |
||
| Mean ± SD | 1.179 ± 0.13 | 2.427 ± 0.597 | 1.062 ± 0.264 | < 0.0001*** | < 0.0001 | 0.0527 (ns) | < 0.0001 |
| Median | 1.150 | 2.330 | 1.035 | ||||
|
Min–Max SE |
1.0 – 1.34 0.02 |
1.03 – 3.31 0.09 |
0.84 – 2.01 0.04 |
||||
Fold Change represents the variations in levels of differentially expressed miRNA-101 in HCV-associated liver diseases between the studied groups and the control. SE Std. Error of Mean SD, standard deviation; miRNA, microRNA