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. 2024 Nov 28;36(1):102408. doi: 10.1016/j.omtn.2024.102408

Figure 3.

Figure 3

Maternal Axl knockout leads to abnormal interface in Axl−/− mice

(A) Utero-placental interface structure of different mating strategies by H&E staining. Black arrows point to foci of glycogen deposition. Black asterisks mark the loosened decidual zone, while blue asterisks point to the compacted decidua. These findings were observed in at least three individual samples. (B) The histology of E7.5 implantation sites and polyploid stromal cells in Axl+/+ and Axl−/− females. (C) The expression of decidual marker PRL8A2 at Axl+/+ and Axl−/− implantation sites on E7.5 (n = 3). (D) DNA content quantification of decidual cells by FACS from Axl+/+ and Axl−/− mice on E7.5. (E) Cellular distribution for 2N, 4N, and >4N populations of stromal cells at Axl+/+ (n = 3) and Axl−/− (n = 3) implantation sites on E7.5. Data represent the means ± SEMs. Scale bars, 0.5 mm; ∗p < 0.05. DB, decidua basalis; Em, embryo; JZ, junctional zone; Lab, labyrinth.