Fig. 4.

Course of mean handgrip strength (Fmean) in % in female patients (n = 13) measured a) initially and then b) repeated after one hour over the study period. The duration of IA therapy is indicated by the green bar. Error bars represent 95% confidence intervals. Data were analyzed using a linear mixed-effects model fitted by restricted maximum likelihood (REML), with t-tests computed using Satterthwaite's method for degrees of freedom with significance levels indicated as ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.